The regulation of appetite and satiety involves a complex interplay of neurological signals played out on many levels: from information originating in the cognitive plane to sensory information coming from peripheral sensory receptors. Peripheral receptors in the form of mechano- and chemo- receptors play a particularly important role in the control of appetite in the immediate postprandial phase of digestion. This review looks at the role played by gut-derived peptides in the relay of this information to the important satiety centre in the brain that helps to control appetite and maintain weight control. |