This article reviews the pivotal role played by homocysteine and associated micronutrient deficiencies in the pathogenesis of Alzheimer’s disease, arguing that modulation of these factors is central to a nutritional understanding of the disease and that supplementation may hold out the prospect of being able to prevent or control the disease. Research into the key role played by homocysteine in Alzheimer’s is probably the most significant finding of recent research in this area. |